MGP Database

MGP001280

Ontology/Pathway Information

Entrez Gene ID	2821
Gene Name	glucose-6-phosphate isomerase
Gene Symbol	GPI
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:HPA	C	cytoplasm
GO:0005829	TAS:Reactome	C	cytosol
GO:0005615	IEA:UniProtKB-KW	C	extracellular space
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0016020	IDA:UniProtKB	C	membrane
GO:0043005	IEA:Ensembl	C	neuron projection
GO:0005654	IDA:HPA	C	nucleoplasm
GO:0005886	IDA:HPA	C	plasma membrane
GO:0004347	TAS:Reactome	F	glucose-6-phosphate isomerase activity
GO:0016866	IEA:Ensembl	F	intramolecular transferase activity
GO:0048029	IEA:Ensembl	F	monosaccharide binding
GO:0046185	IEA:Ensembl	P	aldehyde catabolic process
GO:0001525	IEA:UniProtKB-KW	P	angiogenesis
GO:0005975	TAS:Reactome	P	carbohydrate metabolic process
GO:0006094	TAS:Reactome	P	gluconeogenesis
GO:0051156	IEA:Ensembl	P	glucose 6-phosphate metabolic process
GO:0006006	TAS:Reactome	P	glucose metabolic process
GO:0006096	TAS:Reactome	P	glycolytic process
GO:0007599	TAS:ProtInc	P	hemostasis
GO:0006959	TAS:ProtInc	P	humoral immune response
GO:0007611	IEA:Ensembl	P	learning or memory
GO:0019242	IEA:Ensembl	P	methylglyoxal biosynthetic process
GO:0043154	IEA:Ensembl	P	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043524	IEA:Ensembl	P	negative regulation of neuron apoptotic process
GO:0044281	TAS:Reactome	P	small molecule metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_116125	Disease
REACT_1520	Gluconeogenesis
REACT_723	Glucose metabolism
REACT_264090	Glycogen storage diseases
REACT_1383	Glycolysis
REACT_111217	Metabolism
REACT_474	Metabolism of carbohydrates
REACT_264430	Myoclonic epilepsy of Lafora

SMP Pathway Links

SMP ID	Description
SMP00572	Fanconi-bickel syndrome
SMP00562	Fructose-1,6-diphosphatase deficiency
SMP00128	Gluconeogenesis
SMP00518	Glucose-6-phosphate dehydrogenase deficiency
SMP00581	Glycogenosis, Type IA. Von gierke disease
SMP00573	Glycogenosis, Type IB
SMP00574	Glycogenosis, Type IC
SMP00553	Glycogenosis, Type III. Cori disease, Debrancher glycogenosis
SMP00554	Glycogenosis, Type IV. Amylopectinosis, Anderson disease
SMP00555	Glycogenosis, Type VI. Hers disease
SMP00531	Glycogenosis, Type VII. Tarui disease
SMP00374	Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease
SMP00552	Glycogen synthetase deficiency
SMP00040	Glycolysis
SMP00556	Mucopolysaccharidosis VI. Sly syndrome
SMP00031	Pentose Phosphate Pathway
SMP00560	Phosphoenolpyruvate carboxykinase deficiency 1 (PEPCK1)
SMP00519	Ribose-5-phosphate isomerase deficiency
SMP00058	Starch and Sucrose Metabolism
SMP00557	Sucrase-isomaltase deficiency
SMP00520	Transaldolase deficiency
SMP00563	Triosephosphate isomerase
SMP00654	Warburg Effect