MGP Database

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MGP001314

Ontology/Pathway Information

Entrez Gene ID2891
Gene Nameglutamate receptor, ionotropic, AMPA 2
Gene Symbol GRIA2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0032281 ISS:UniProtKBCalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0030054 IEA:UniProtKB-KWCcell junction
GO:0030425 IBA:GO_CentralCdendrite
GO:0030666 TAS:ReactomeCendocytic vesicle membrane
GO:0005789 IEA:UniProtKB-SubCellCendoplasmic reticulum membrane
GO:0005887 ISS:UniProtKBCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0045211 IBA:GO_CentralCpostsynaptic membrane
GO:0008021 IEA:EnsemblCsynaptic vesicle
GO:0004971 ISS:UniProtKBFalpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0005234 IBA:GO_CentralFextracellular-glutamate-gated ion channel activity
GO:0004970 IDA:UniProtKBFionotropic glutamate receptor activity
GO:0035235 IDA:UniProtKBPionotropic glutamate receptor signaling pathway
GO:0034220 IBA:GOCPion transmembrane transport
GO:0007165 TAS:ProtIncPsignal transduction
GO:0007268 TAS:ReactomePsynaptic transmission
GO:0035249 IBA:GO_CentralPsynaptic transmission, glutamatergic
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18338Activation of AMPA receptors
REACT_20563Activation of NMDA receptor upon glutamate binding and postsynaptic events
REACT_18347Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
REACT_13685Neuronal System
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_18307Trafficking of AMPA receptors
REACT_18422Trafficking of GluR2-containing AMPA receptors
REACT_13477Transmission across Chemical Synapses
REACT_20594Unblocking of NMDA receptor, glutamate binding and activation
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