MGP Database

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MGP001343

Record overview

MGPD IDMGP001343
Gene ID2931
SpeciesHomo sapiens (Human)
Gene Nameglycogen synthase kinase 3 alpha
Gene Symbol GSK3A
Alternate namesglycogen synthase kinase-3 alpha; GSK-3 alpha; serine/threonine-protein kinase GSK3A;
Chromosome19
Map Location19q13.2
EC Number2.7.11.26
SummaryThis gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011]
OrthologsView orthologs and multiple alignments for GSK3A

Proteins

glycogen synthase kinase-3 alpha
Refseq ID:NP_063937
Protein GI:49574532
UniProt ID:P49840
mRNA ID:NM_019884
Length:483
RefSeq Status:
MSGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPGGSGGGGSGGPGAGTSFPPPGVKLGRDSGKV
TTVVATLGQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPE
TVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSS
IDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAH
SFFDELRCLGTQLPNNRPLPPLFNFSAGELSIQPSLNAILIPPHLRSPAGTTTLTPSSQALTETPTSSDWQSTDATPTLTNSS
 
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