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MGP001349

UniProt Annotations

Entry Information
Gene Nameglutathione S-transferase alpha 2
Protein EntryGSTA2_HUMAN
UniProt IDP09210
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityRX + glutathione = HX + R-S-glutathione.
FunctionConjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
SimilarityBelongs to the GST superfamily. Alpha family. {ECO:0000305}.
SimilarityContains 1 GST C-terminal domain. {ECO:0000305}.
SimilarityContains 1 GST N-terminal domain. {ECO:0000305}.
Subcellular LocationCytoplasm.
SubunitHomodimer or heterodimer of GSTA1 and GSTA2. {ECO:0000269|PubMed:20083122, ECO:0000269|PubMed:7892174}.
Tissue SpecificityLiver.
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