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MGP001355

UniProt Annotations

Entry Information
Gene Nameglutathione S-transferase mu 4
Protein EntryGSTM4_HUMAN
UniProt IDQ03013
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q03013-1; Sequence=Displayed; Name=2; IsoId=Q03013-2; Sequence=VSP_011773, VSP_011774; Name=3; IsoId=Q03013-3; Sequence=VSP_047688;
Catalytic ActivityRX + glutathione = HX + R-S-glutathione.
FunctionConjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Active on 1- chloro-2,4-dinitrobenzene.
SimilarityBelongs to the GST superfamily. Mu family. {ECO:0000305}.
SimilarityContains 1 GST C-terminal domain. {ECO:0000305}.
SimilarityContains 1 GST N-terminal domain. {ECO:0000305}.
Subcellular LocationCytoplasm.
SubunitHomodimer.
Tissue SpecificityExpressed in a wide variety of tissues.
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