MGP Database

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MGP001377

Ontology/Pathway Information

Entrez Gene ID2977
Gene Nameguanylate cyclase 1, soluble, alpha 2
Gene Symbol GUCY1A2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IEA:UniProtKB-SubCellCcytoplasm
GO:0005525 IEA:UniProtKB-KWFGTP binding
GO:0004383 TAS:ProtIncFguanylate cyclase activity
GO:0020037 IEA:InterProFheme binding
GO:0007596 TAS:ReactomePblood coagulation
GO:0035556 IEA:InterProPintracellular signal transduction
GO:0030828 IEA:EnsemblPpositive regulation of cGMP biosynthetic process
GO:0007165 TAS:ProtIncPsignal transduction
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_604Hemostasis
REACT_23862Nitric oxide stimulates guanylate cyclase
REACT_23876Platelet homeostasis
SMP Pathway Links
SMP IDDescription
SMP00535Adenine phosphoribosyltransferase deficiency (APRT)
SMP00144Adenosine Deaminase Deficiency
SMP00167Adenylosuccinate Lyase Deficiency
SMP00168AICA-Ribosiduria
SMP00427Azathioprine Action Pathway
SMP00365Gout or Kelley-Seegmiller Syndrome
SMP00364Lesch-Nyhan Syndrome (LNS)
SMP00428Mercaptopurine Action Pathway
SMP00536Mitochondrial DNA depletion syndrome
SMP00203Molybdenum Cofactor Deficiency
SMP00537Myoadenylate deaminase deficiency
SMP00050Purine Metabolism
SMP00210Purine Nucleoside Phosphorylase Deficiency
SMP00430Thioguanine Action Pathway
SMP00220Xanthine Dehydrogenase Deficiency (Xanthinuria)
SMP00512Xanthinuria type I
SMP00513Xanthinuria type II
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