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MGP001379

UniProt Annotations

Entry Information
Gene Nameguanylate cyclase 1, soluble, alpha 3
Protein Entry
UniProt ID
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q02108-1; Sequence=Displayed; Name=2; IsoId=Q02108-2; Sequence=VSP_045477; Note=No experimental confirmation available.;
Catalytic ActivityGTP = 3',5'-cyclic GMP + diphosphate.
Enzyme RegulationActivated by nitric oxide in the presence of magnesium or manganese ions.
MiscellaneousThere are two types of guanylate cyclases: soluble forms and membrane-associated receptor forms.
Sequence CautionSequence=CAA47145.1; Type=Frameshift; Positions=123, 127, 131, 162, 184, 529, 535, 678, 680; Evidence={ECO:0000305};
SimilarityBelongs to the adenylyl cyclase class-4/guanylyl cyclase family. {ECO:0000255|PROSITE-ProRule:PRU00099}.
SimilarityContains 1 guanylate cyclase domain. {ECO:0000255|PROSITE-ProRule:PRU00099}.
Subcellular LocationCytoplasm.
SubunitHeterodimer of an alpha and a beta chain.
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