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MGP001392

Record overview

MGPD IDMGP001392
Gene ID3006
SpeciesHomo sapiens (Human)
Gene Namehistone cluster 1, H1c
Gene Symbol HIST1H1C
SynonymsH1C; H1.2; H1F2; H1s-1;
Alternate nameshistone H1.2; H1 histone family, member 2; histone 1, H1c; histone H1c; histone H1d; histone H1s-1;
Chromosome6
Map Location6p21.3
SummaryHistones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for HIST1H1C

Proteins

histone H1.2
Refseq ID:NP_005310
Protein GI:4885375
UniProt ID:P16403
mRNA ID:NM_005319
Length:213
RefSeq Status:
MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTG
ASGSFKLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKP
KVVKPKKAAPKKK
 
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