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MGP001398

Record overview

MGPD IDMGP001398
Gene ID3014
SpeciesHomo sapiens (Human)
Gene NameH2A histone family, member X
Gene Symbol H2AFX
SynonymsH2AX; H2A.X; H2A/X;
Alternate nameshistone H2AX; H2AX histone; histone H2A.x;
Chromosome11
Map Location11q23.3
SummaryHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for H2AFX

Proteins

histone H2AX
Refseq ID:NP_002096
Protein GI:4504253
UniProt ID:P16104
mRNA ID:NM_002105
Length:143
RefSeq Status:
MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGG
VTIAQGGVLPNIQAVLLPKKTSATVGPKAPSGGKKATQASQEY
 
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