MGP Database

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MGP001440

Ontology/Pathway Information

Entrez Gene ID3099
Gene Namehexokinase 2
Gene Symbol HK2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0016020 IDA:UniProtKBCmembrane
GO:0005741 IDA:MGICmitochondrial outer membrane
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0008865 IBA:GO_CentralFfructokinase activity
GO:0004340 IBA:GO_CentralFglucokinase activity
GO:0005536 IEA:EnsemblFglucose binding
GO:0004396 TAS:ProtIncFhexokinase activity
GO:0019158 IBA:GO_CentralFmannokinase activity
GO:0008637 IDA:MGIPapoptotic mitochondrial changes
GO:0005975 TAS:ReactomePcarbohydrate metabolic process
GO:0001678 IBA:GO_CentralPcellular glucose homeostasis
GO:0051156 IBA:GOCPglucose 6-phosphate metabolic process
GO:0006006 IEA:EnsemblPglucose metabolic process
GO:0015758 TAS:ReactomePglucose transport
GO:0006096 IBA:GO_CentralPglycolytic process
GO:0008645 TAS:ReactomePhexose transport
GO:0007595 IEA:EnsemblPlactation
GO:0046324 IEA:EnsemblPregulation of glucose import
GO:0002931 IEA:EnsemblPresponse to ischemia
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0055085 TAS:ReactomePtransmembrane transport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_116125Disease
REACT_212Glucose transport
REACT_264090Glycogen storage diseases
REACT_9441Hexose transport
REACT_111217Metabolism
REACT_474Metabolism of carbohydrates
REACT_264430Myoclonic epilepsy of Lafora
REACT_19118SLC-mediated transmembrane transport
REACT_15518Transmembrane transport of small molecules
SMP Pathway Links
SMP IDDescription
SMP00572Fanconi-bickel syndrome
SMP00562Fructose-1,6-diphosphatase deficiency
SMP00128Gluconeogenesis
SMP00581Glycogenosis, Type IA. Von gierke disease
SMP00573Glycogenosis, Type IB
SMP00574Glycogenosis, Type IC
SMP00553Glycogenosis, Type III. Cori disease, Debrancher glycogenosis
SMP00554Glycogenosis, Type IV. Amylopectinosis, Anderson disease
SMP00555Glycogenosis, Type VI. Hers disease
SMP00531Glycogenosis, Type VII. Tarui disease
SMP00374Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease
SMP00552Glycogen synthetase deficiency
SMP00040Glycolysis
SMP00556Mucopolysaccharidosis VI. Sly syndrome
SMP00560Phosphoenolpyruvate carboxykinase deficiency 1 (PEPCK1)
SMP00058Starch and Sucrose Metabolism
SMP00557Sucrase-isomaltase deficiency
SMP00563Triosephosphate isomerase
SMP00654Warburg Effect
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