MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP001443

Ontology/Pathway Information

Entrez Gene ID3106
Gene Namemajor histocompatibility complex, class I, B
Gene Symbol HLA-B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 ISS:UniProtKBCcell surface
GO:0031901 TAS:ReactomeCearly endosome membrane
GO:0005783 IDA:UniProtKBCendoplasmic reticulum
GO:0012507 TAS:ReactomeCER to Golgi transport vesicle membrane
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005794 IDA:UniProtKBCGolgi apparatus
GO:0000139 TAS:ReactomeCGolgi membrane
GO:0071556 TAS:ReactomeCintegral component of lumenal side of endoplasmic reticulum membrane
GO:0005887 NAS:UniProtKBCintegral component of plasma membrane
GO:0016020 IDA:UniProtKBCmembrane
GO:0042612 ISS:UniProtKBCMHC class I protein complex
GO:0030670 TAS:ReactomeCphagocytic vesicle membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0042605 ISS:UniProtKBFpeptide antigen binding
GO:0005102 IPI:UniProtKBFreceptor binding
GO:0042590 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0002474 TAS:ReactomePantigen processing and presentation of peptide antigen via MHC class I
GO:0019221 TAS:ReactomePcytokine-mediated signaling pathway
GO:0006955 NAS:UniProtKBPimmune response
GO:0060333 TAS:ReactomePinterferon-gamma-mediated signaling pathway
GO:0001916 IEA:InterProPpositive regulation of T cell mediated cytotoxicity
GO:0042270 IDA:UniProtKBPprotection from natural killer cell mediated cytotoxicity
GO:2001198 IMP:BHF-UCLPregulation of dendritic cell differentiation
GO:0050776 TAS:ReactomePregulation of immune response
GO:0032655 IMP:BHF-UCLPregulation of interleukin-12 production
GO:0032675 IMP:BHF-UCLPregulation of interleukin-6 production
GO:0002667 IMP:BHF-UCLPregulation of T cell anergy
GO:0060337 TAS:ReactomePtype I interferon signaling pathway
GO:0016032 IEA:UniProtKB-KWPviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_75795Antigen Presentation: Folding, assembly and peptide loading of class I MHC
REACT_111119Antigen processing-Cross presentation
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_75790Cytokine Signaling in Immune system
REACT_111168Endosomal/Vacuolar pathway
REACT_111178ER-Phagosome pathway
REACT_6900Immune System
REACT_11152Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
REACT_25162Interferon alpha/beta signaling
REACT_25078Interferon gamma signaling
REACT_25229Interferon Signaling
  logo