MGP Database

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MGP001459

Ontology/Pathway Information

Entrez Gene ID3134
Gene Namemajor histocompatibility complex, class I, F
Gene Symbol HLA-F
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:UniProtKBCcell surface
GO:0031901 TAS:ReactomeCearly endosome membrane
GO:0005783 IDA:UniProtKBCendoplasmic reticulum
GO:0012507 TAS:ReactomeCER to Golgi transport vesicle membrane
GO:0000139 TAS:ReactomeCGolgi membrane
GO:0071556 TAS:ReactomeCintegral component of lumenal side of endoplasmic reticulum membrane
GO:0016020 IDA:UniProtKBCmembrane
GO:0042612 IEA:UniProtKB-KWCMHC class I protein complex
GO:0030670 TAS:ReactomeCphagocytic vesicle membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0042605 IBA:GO_CentralFpeptide antigen binding
GO:0005102 IBA:GO_CentralFreceptor binding
GO:0046978 IPI:UniProtKBFTAP1 binding
GO:0046979 IPI:UniProtKBFTAP2 binding
GO:0042590 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0002474 TAS:ReactomePantigen processing and presentation of peptide antigen via MHC class I
GO:0019221 TAS:ReactomePcytokine-mediated signaling pathway
GO:0060333 TAS:ReactomePinterferon-gamma-mediated signaling pathway
GO:0001916 IEA:InterProPpositive regulation of T cell mediated cytotoxicity
GO:0050776 TAS:ReactomePregulation of immune response
GO:0060337 TAS:ReactomePtype I interferon signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_75795Antigen Presentation: Folding, assembly and peptide loading of class I MHC
REACT_111119Antigen processing-Cross presentation
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_75790Cytokine Signaling in Immune system
REACT_111168Endosomal/Vacuolar pathway
REACT_111178ER-Phagosome pathway
REACT_6900Immune System
REACT_11152Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
REACT_25162Interferon alpha/beta signaling
REACT_25078Interferon gamma signaling
REACT_25229Interferon Signaling
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