MGP Database

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MGP001459

UniProt Annotations

Entry Information
Gene Namemajor histocompatibility complex, class I, F
Protein EntryHLAF_HUMAN
UniProt IDP30511
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; IsoId=P30511-1; Sequence=Displayed; Name=2; IsoId=P30511-2; Sequence=VSP_038846; Name=3; IsoId=P30511-3; Sequence=VSP_040349; Note=Ref.10 (AAH09260) sequence is in conflict in position: 353:N->L. {ECO:0000305};
FunctionInvolved in the presentation of foreign antigens to the immune system.
Sequence CautionSequence=AAC24827.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAH09260.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAB63337.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAA34947.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAB46623.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the MHC class I family. {ECO:0000305}.
SimilarityContains 1 Ig-like C1-type (immunoglobulin-like) domain. {ECO:0000305}.
Subcellular LocationMembrane; Single-pass type I membrane protein.
SubunitHeterodimer of an alpha chain and a beta chain (beta-2- microglobulin).
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