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MGP001471

Record overview

MGPD IDMGP001471
Gene ID3162
SpeciesHomo sapiens (Human)
Gene Nameheme oxygenase (decycling) 1
Gene Symbol HMOX1
SynonymsHO-1; HSP32; HMOX1D; bK286B10;
Alternate namesheme oxygenase 1; heat shock protein, 32-kD;
Chromosome22
Map Location22q13.1
EC Number1.14.99.3;
SummaryHeme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for HMOX1

Proteins

heme oxygenase 1
Refseq ID:NP_002124
Protein GI:4504437
UniProt ID:P09601
mRNA ID:NM_002133
Length:288
RefSeq Status:
MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPR
WQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVI
EEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRASNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATVAVGLYAM
 
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