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MGP001486

Record overview

MGPD IDMGP001486
Gene ID3187
SpeciesHomo sapiens (Human)
Gene Nameheterogeneous nuclear ribonucleoprotein H1 (H)
Gene Symbol HNRNPH1
SynonymsHNRPH; HNRPH1; hnRNPH;
Alternate namesheterogeneous nuclear ribonucleoprotein H;
Chromosome5
Map Location5q35.3
SummaryThis gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described [provided by RefSeq, Mar 2012]
OrthologsView orthologs and multiple alignments for HNRNPH1

Proteins

heterogeneous nuclear ribonucleoprotein H
Refseq ID:NP_001244222
Protein GI:381342476
UniProt ID:P31943
mRNA ID:NM_001257293
Length:449
RefSeq Status:
MMLGTEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHT
GPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRK
LMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRA
TENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGM
GLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQENSSDFQSNIA
 
heterogeneous nuclear ribonucleoprotein H
Refseq ID:NP_005511
Protein GI:5031753
UniProt ID:P31943
mRNA ID:NM_005520
Length:449
RefSeq Status:
Protein sequence is identical to GI:381342476 (mRNA isoform)
 
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