MGP Database

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MGP001500

Ontology/Pathway Information

Entrez Gene ID3274
Gene Namehistamine receptor H2
Gene Symbol HRH2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0004969 TAS:ProtIncFhistamine receptor activity
GO:0048565 IEA:EnsemblPdigestive tract development
GO:0003382 IEA:EnsemblPepithelial cell morphogenesis
GO:0001698 IEA:EnsemblPgastrin-induced gastric acid secretion
GO:0048732 IEA:EnsemblPgland development
GO:0007187 TAS:ProtIncPG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0001697 IEA:EnsemblPhistamine-induced gastric acid secretion
GO:0006955 TAS:ProtIncPimmune response
GO:0007613 IEA:EnsemblPmemory
GO:0045907 IEA:InterProPpositive regulation of vasoconstriction
GO:0048167 IEA:EnsemblPregulation of synaptic plasticity
GO:0008542 IEA:EnsemblPvisual learning
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_16983Amine ligand-binding receptors
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19327G alpha (s) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_16903Histamine receptors
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00736Betazole Action Pathway
SMP00232Cimetidine Action Pathway
SMP00617Cimetidine Metabolism Pathway
SMP00225Esomeprazole Action Pathway
SMP00231Famotidine Action Pathway
SMP00589Gastric Acid Production
SMP00335Intracellular Signalling Through Histamine H2 Receptor and Histamine
SMP00227Lansoprazole Action Pathway
SMP00735Metiamide Action Pathway
SMP00233Nizatidine Action Pathway
SMP00226Omeprazole Action Pathway
SMP00228Pantoprazole Action Pathway
SMP00246Pirenzepine Action Pathway
SMP00229Rabeprazole Action Pathway
SMP00230Ranitidine Action Pathway
SMP00734Roxatidine acetate Action Pathway
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