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MGP001519

Record overview

MGPD IDMGP001519
Gene ID3315
SpeciesHomo sapiens (Human)
Gene Nameheat shock 27kDa protein 1
Gene Symbol HSPB1
SynonymsCMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067; HEL-S-102;
Alternate namesheat shock protein beta-1; 28 kDa heat shock protein; HSP 27; epididymis secretory protein Li 102; estrogen-regulated 24 kDa protein; heat shock 27 kDa protein; heat shock 27kD protein 1; stress-responsive protein 27;
Chromosome7
Map Location7q11.23
SummaryThe protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). [provided by RefSeq, Oct 2008]
OrthologsView orthologs and multiple alignments for HSPB1

Proteins

heat shock protein beta-1
Refseq ID:NP_001531
Protein GI:4504517
UniProt ID:P04792
mRNA ID:NM_001540
Length:205
RefSeq Status:
MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLD
VNHFAPDELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEITIPVTFESRAQLGGPEAAKSD
ETAAK
 
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