MGP Database

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MGP001519

Ontology/Pathway Information

Entrez Gene ID3315
Gene Nameheat shock 27kDa protein 1
Gene Symbol HSPB1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005856 TAS:UniProtKBCcytoskeleton
GO:0005829 TAS:ReactomeCcytosol
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 IEA:EnsemblCplasma membrane
GO:0000502 ISS:BHF-UCLCproteasome complex
GO:0005819 IEA:UniProtKB-SubCellCspindle
GO:0030018 IEA:EnsemblCZ disc
GO:0042802 IPI:IntActFidentical protein binding
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0019901 IPI:UniProtKBFprotein kinase binding
GO:0005080 ISS:BHF-UCLFprotein kinase C binding
GO:0008426 ISS:BHF-UCLFprotein kinase C inhibitor activity
GO:0043130 ISS:BHF-UCLFubiquitin binding
GO:0006928 TAS:UniProtKBPcellular component movement
GO:0035924 IMP:BHF-UCLPcellular response to vascular endothelial growth factor stimulus
GO:0010467 TAS:ReactomePgene expression
GO:0035556 IMP:BHF-UCLPintracellular signal transduction
GO:0016071 TAS:ReactomePmRNA metabolic process
GO:0043066 TAS:UniProtKBPnegative regulation of apoptotic process
GO:1902176 ISS:BHF-UCLPnegative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0006469 ISS:BHF-UCLPnegative regulation of protein kinase activity
GO:0070527 IMP:UniProtKBPplatelet aggregation
GO:0045766 IMP:BHF-UCLPpositive regulation of angiogenesis
GO:0043536 IMP:BHF-UCLPpositive regulation of blood vessel endothelial cell migration
GO:2001028 IMP:BHF-UCLPpositive regulation of endothelial cell chemotaxis
GO:0038033 IMP:BHF-UCLPpositive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
GO:0032731 ISS:BHF-UCLPpositive regulation of interleukin-1 beta production
GO:0042535 ISS:BHF-UCLPpositive regulation of tumor necrosis factor biosynthetic process
GO:0043122 ISS:BHF-UCLPregulation of I-kappaB kinase/NF-kappaB signaling
GO:0006446 TAS:ProtIncPregulation of translational initiation
GO:0006986 NAS:UniProtKBPresponse to unfolded protein
GO:0009615 IEP:UniProtKBPresponse to virus
GO:0001895 IEP:UniProtKBPretina homeostasis
GO:0016070 TAS:ReactomePRNA metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_25325AUF1 (hnRNP D0) destabilizes mRNA
REACT_71Gene Expression
REACT_24994Regulation of mRNA stability by proteins that bind AU-rich elements
REACT_12529Signaling by VEGF
REACT_111102Signal Transduction
REACT_264464VEGFA-VEGFR2 Pathway
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