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MGP001526

Record overview

MGPD IDMGP001526
Gene ID3350
SpeciesHomo sapiens (Human)
Gene Name5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
Gene Symbol HTR1A
SynonymsG-21; 5HT1a; PFMCD; 5-HT1A; 5-HT-1A; ADRBRL1; ADRB2RL1;
Alternate names5-hydroxytryptamine receptor 1A; 5-HT1a receptor; guanine nucleotide-binding regulatory protein-coupled receptor;
Chromosome5
Map Location5q11.2-q13
SummaryThis gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
OrthologsView orthologs and multiple alignments for HTR1A

Proteins

5-hydroxytryptamine receptor 1A
Refseq ID:NP_000515
Protein GI:55956923
UniProt ID:P08908
mRNA ID:NM_000524
Length:422
RefSeq Status:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLN
KWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYST
FGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIY
AYFNKDFQNAFKKIIKCKFCRQ
 
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