MGP Database

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MGP001526

Ontology/Pathway Information

Entrez Gene ID3350
Gene Name5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
Gene Symbol HTR1A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005887 IDA:UniProtKBCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0004993 IDA:UniProtKBFserotonin receptor activity
GO:0007198 IDA:UniProtKBPadenylate cyclase-inhibiting serotonin receptor signaling pathway
GO:0001662 ISS:UniProtKBPbehavioral fear response
GO:0008283 IEA:InterProPcell proliferation
GO:0035640 ISS:UniProtKBPexploration behavior
GO:0007186 IMP:UniProtKBPG-protein coupled receptor signaling pathway
GO:0008284 TAS:ProtIncPpositive regulation of cell proliferation
GO:0050795 IEA:InterProPregulation of behavior
GO:0042053 ISS:UniProtKBPregulation of dopamine metabolic process
GO:0046883 IEA:InterProPregulation of hormone secretion
GO:0014062 ISS:UniProtKBPregulation of serotonin secretion
GO:0042428 ISS:UniProtKBPserotonin metabolic process
GO:0007210 ISS:UniProtKBPserotonin receptor signaling pathway
GO:0042310 IEA:InterProPvasoconstriction
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_16983Amine ligand-binding receptors
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_17064Serotonin receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP006793-Methylthiofentanyl Action Pathway
SMP00413Alfentanil Action Pathway
SMP00685Alvimopan Action Pathway
SMP00674Anileridine Action Pathway
SMP00392Benzocaine Action Pathway
SMP00393Bupivacaine Action Pathway
SMP00684Buprenorphine Action Pathway
SMP00414Carfentanil Action Pathway
SMP00394Chloroprocaine Action Pathway
SMP00424Citalopram Action Pathway
SMP00395Cocaine Action Pathway
SMP00405Codeine Action Pathway
SMP00423Desipramine Action Pathway
SMP00676Dezocine Action Pathway
SMP00396Dibucaine Action Pathway
SMP00689Dihydromorphine Action Pathway
SMP00680Dimethylthiambutene Action Pathway
SMP00675Diphenoxylate Action Pathway
SMP00425Escitalopram Action Pathway
SMP00681Ethylmorphine Action Pathway
SMP00415Fentanyl Action Pathway
SMP00426Fluoxetine Action Pathway
SMP00407Heroin Action Pathway
SMP00411Hydrocodone Action Pathway
SMP00410Hydromorphone Action Pathway
SMP00422Imipramine Action Pathway
SMP00690Ketobemidone Action Pathway
SMP00683Levallorphan Action Pathway
SMP00397Levobupivacaine Action Pathway
SMP00677Levomethadyl Acetate Action Action Pathway
SMP00673Levorphanol Action Pathway
SMP00398Lidocaine (Local Anaesthetic) Action Pathway
SMP00399Mepivacaine Action Pathway
SMP00408Methadone Action Pathway
SMP00678Methadyl Acetate Action Pathway
SMP00406Morphine Action Pathway
SMP00691Nalbuphine Action Pathway
SMP00688Naloxone Action Pathway
SMP00687Naltrexone Action Pathway
SMP00431Nicotine Action Pathway
SMP00400Oxybuprocaine Action Pathway
SMP00409Oxycodone Action Pathway
SMP00412Oxymorphone Action Pathway
SMP00686Pentazocine Action Pathway
SMP00401Prilocaine Action Pathway
SMP00402Procaine Action Pathway
SMP00403Proparacaine Action Pathway
SMP00672Propoxyphene Action Pathway
SMP00416Remifentanil Action Pathway
SMP00404Ropivacaine Action Pathway
SMP00417Sufentanil Action Pathway
SMP00671Tramadol Action Action Pathway
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