MGP Database

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MGP001546

Record overview

MGPD IDMGP001546
Gene ID3384
SpeciesHomo sapiens (Human)
Gene Nameintercellular adhesion molecule 2
Gene Symbol ICAM2
SynonymsCD102;
Alternate namesintercellular adhesion molecule 2; ICAM-2;
Chromosome17
Map Location17q23.3
SummaryThe protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ICAM2

Proteins

intercellular adhesion molecule 2 precursor
Refseq ID:NP_001093256
Protein GI:153082686
UniProt ID:P13598
mRNA ID:NM_001099786
Length:275
RefSeq Status:
MSSFGYRTLTVALFTLICCPGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQE
SMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRG
GNIFHKHSAPKMLEIYEPVSDSQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP
 
sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP

sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP
 
intercellular adhesion molecule 2 precursor
Refseq ID:NP_001093257
Protein GI:153082699
UniProt ID:P13598
mRNA ID:NM_001099787
Length:275
RefSeq Status:
Protein sequence is identical to GI:153082686 (mRNA isoform)
 
sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP
 
intercellular adhesion molecule 2 precursor
Refseq ID:NP_001093258
Protein GI:153082719
UniProt ID:P13598
mRNA ID:NM_001099788
Length:275
RefSeq Status:
Protein sequence is identical to GI:153082686 (mRNA isoform)
 
sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP

sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP

sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP

sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP

sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP
 
intercellular adhesion molecule 2 precursor
Refseq ID:NP_001093259
Protein GI:153082722
UniProt ID:P13598
mRNA ID:NM_001099789
Length:275
RefSeq Status:
Protein sequence is identical to GI:153082686 (mRNA isoform)
 
sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP

sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP

sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP

sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP
 
intercellular adhesion molecule 2 precursor
Refseq ID:NP_000864
Protein GI:153082696
UniProt ID:P13598
mRNA ID:NM_000873
Length:275
RefSeq Status:
Protein sequence is identical to GI:153082686 (mRNA isoform)
 
sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP

sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP

sig_peptide: 1..21
calculated_mol_wt: 2281
peptide sequence: 
MSSFGYRTLTVALFTLICCPG

mat_peptide: 22..275
product: intercellular adhesion molecule 2
calculated_mol_wt: 28392
peptide sequence: 
SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQP
TLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSD
SQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP
 
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