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MGP001551

Record overview

MGPD IDMGP001551
Gene ID3397
SpeciesHomo sapiens (Human)
Gene Nameinhibitor of DNA binding 1, dominant negative helix-loop-helix protein
Gene Symbol ID1
SynonymsID; bHLHb24;
Alternate namesDNA-binding protein inhibitor ID-1; class B basic helix-loop-helix protein 24; dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein); inhibitor of differentiation 1;
Chromosome20
Map Location20q11
SummaryThe protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ID1

Proteins

DNA-binding protein inhibitor ID-1 isoform a
Refseq ID:NP_002156
Protein GI:31317299
UniProt ID:P41134
mRNA ID:NM_002165
Length:155
RefSeq Status:
MKVASGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAGGAGARLPALLDEQQVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVID
YIRDLQLELNSESEVGTPGGRGLPVRAPLSTLNGEISALTAEAACVPADDRILCR
 
DNA-binding protein inhibitor ID-1 isoform b
Refseq ID:NP_851998
Protein GI:31317297
UniProt ID:P41134
mRNA ID:NM_181353
Length:149
RefSeq Status:
MKVASGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAGGAGARLPALLDEQQVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVID
YIRDLQLELNSESEVGTPGGRGLPVRAPLSTLNGEISALTAEVRSRSDH
 
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