MGP Database

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MGP001590

Ontology/Pathway Information

Entrez Gene ID3484
Gene Nameinsulin-like growth factor binding protein 1
Gene Symbol IGFBP1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IBA:GO_CentralCextracellular space
GO:0005520 TAS:ProtIncFinsulin-like growth factor binding
GO:0031994 IBA:GO_CentralFinsulin-like growth factor I binding
GO:0031995 IBA:GO_CentralFinsulin-like growth factor II binding
GO:0006987 TAS:ReactomePactivation of signaling protein activity involved in unfolded protein response
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0030968 TAS:ReactomePendoplasmic reticulum unfolded protein response
GO:0008286 IEA:EnsemblPinsulin receptor signaling pathway
GO:0030307 IEA:EnsemblPpositive regulation of cell growth
GO:0043567 IBA:GO_CentralPregulation of insulin-like growth factor receptor signaling pathway
GO:0007165 TAS:ProtIncPsignal transduction
GO:0042246 IEA:EnsemblPtissue regeneration
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18355ATF4 activates genes
REACT_17015Metabolism of proteins
REACT_18277PERK regulates gene expression
REACT_15428Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
REACT_18356Unfolded Protein Response (UPR)
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