MGP Database

MGP001591

Ontology/Pathway Information

Entrez Gene ID	3485
Gene Name	insulin-like growth factor binding protein 2, 36kDa
Gene Symbol	IGFBP2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0016324	IEA:Ensembl	C	apical plasma membrane
GO:0031410	IEA:Ensembl	C	cytoplasmic vesicle
GO:0005576	ISS:UniProtKB	C	extracellular region
GO:0005615	IDA:BHF-UCL	C	extracellular space
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0031994	IDA:UniProtKB	F	insulin-like growth factor I binding
GO:0031995	ISS:UniProtKB	F	insulin-like growth factor II binding
GO:0007568	IEA:Ensembl	P	aging
GO:0044267	TAS:Reactome	P	cellular protein metabolic process
GO:0032870	IEA:Ensembl	P	cellular response to hormone stimulus
GO:0007565	IEA:Ensembl	P	female pregnancy
GO:0042104	IDA:BHF-UCL	P	positive regulation of activated T cell proliferation
GO:0001558	IEA:InterPro	P	regulation of cell growth
GO:0043567	ISS:UniProtKB	P	regulation of insulin-like growth factor receptor signaling pathway
GO:0042493	IEA:Ensembl	P	response to drug
GO:0032355	IEA:Ensembl	P	response to estradiol
GO:0051384	IEA:Ensembl	P	response to glucocorticoid
GO:0010226	IEA:Ensembl	P	response to lithium ion
GO:0009612	IEA:Ensembl	P	response to mechanical stimulus
GO:0007584	IEA:Ensembl	P	response to nutrient
GO:0032526	IEA:Ensembl	P	response to retinoic acid
GO:0007165	IEA:Ensembl	P	signal transduction

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_17015	Metabolism of proteins
REACT_15428	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)