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MGP001611

UniProt Annotations

Entry Information
Gene Nameinterleukin 5
Protein EntryIL5_HUMAN
UniProt IDP05113
SpeciesHuman
Comments
Comment typeDescription
FunctionFactor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.
InteractionP32927:CSF2RB; NbExp=2; IntAct=EBI-2435811, EBI-1809771; Q01344:IL5RA; NbExp=2; IntAct=EBI-2435811, EBI-1759442;
SimilarityBelongs to the IL-5 family. {ECO:0000305}.
Subcellular LocationSecreted.
SubunitHomodimer; disulfide-linked. {ECO:0000269|PubMed:2037074, ECO:0000269|PubMed:22153509, ECO:0000269|PubMed:2361960, ECO:0000269|PubMed:8483502}.
Web ResourceName=R&D Systems' cytokine mini-reviews: IL-5; URL="http://www.rndsystems.com/molecule_detail.aspx?m=1646";
Web ResourceName=SeattleSNPs; URL="http://pga.gs.washington.edu/data/il5/";
Web ResourceName=Wikipedia; Note=Interleukin-5 entry; URL="http://en.wikipedia.org/wiki/Interleukin_5";
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