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MGP Database

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MGP001640

Ontology/Pathway Information

Entrez Gene ID	3638
Gene Name	insulin induced gene 1
Gene Symbol	INSIG1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005783	IDA:UniProtKB	C	endoplasmic reticulum
GO:0005789	TAS:Reactome	C	endoplasmic reticulum membrane
GO:0032937	IDA:UniProtKB	C	SREBP-SCAP-Insig complex
GO:0008283	TAS:ProtInc	P	cell proliferation
GO:0006695	IEA:Ensembl	P	cholesterol biosynthetic process
GO:0060363	IEA:Ensembl	P	cranial suture morphogenesis
GO:0042472	IEA:Ensembl	P	inner ear morphogenesis
GO:0008152	TAS:ProtInc	P	metabolic process
GO:0042474	IEA:Ensembl	P	middle ear morphogenesis
GO:1901303	IMP:UniProtKB	P	negative regulation of cargo loading into COPII-coated vesicle
GO:0045599	IEA:Ensembl	P	negative regulation of fat cell differentiation
GO:0045717	IEA:Ensembl	P	negative regulation of fatty acid biosynthetic process
GO:0010894	IEA:Ensembl	P	negative regulation of steroid biosynthetic process
GO:0060021	IEA:Ensembl	P	palate development
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0032933	IDA:UniProtKB	P	SREBP signaling pathway
GO:0006641	IEA:Ensembl	P	triglyceride metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_111217	Metabolism
REACT_22258	Metabolism of lipids and lipoproteins
REACT_147797	Regulation of cholesterol biosynthesis by SREBP (SREBF)