MGP Database

MGP001662

Ontology/Pathway Information

Entrez Gene ID	3675
Gene Name	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Gene Symbol	ITGA3
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0016323	IEA:Ensembl	C	basolateral plasma membrane
GO:0071944	IDA:UniProtKB	C	cell periphery
GO:0009986	IDA:UniProtKB	C	cell surface
GO:0009897	IEA:Ensembl	C	external side of plasma membrane
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0031527	IDA:UniProtKB	C	filopodium membrane
GO:0005925	IDA:UniProtKB	C	focal adhesion
GO:0030426	IEA:Ensembl	C	growth cone
GO:0034667	IDA:UniProtKB	C	integrin alpha3-beta1 complex
GO:0008305	TAS:ProtInc	C	integrin complex
GO:0071438	IDA:UniProtKB	C	invadopodium membrane
GO:0048471	IEA:Ensembl	C	perinuclear region of cytoplasm
GO:0005886	IDA:BHF-UCL	C	plasma membrane
GO:0043235	IDA:MGI	C	receptor complex
GO:0045202	IEA:Ensembl	C	synapse
GO:0001948	IPI:UniProtKB	F	glycoprotein binding
GO:0046872	IEA:UniProtKB-KW	F	metal ion binding
GO:0002020	IPI:UniProtKB	F	protease binding
GO:0046982	IDA:UniProtKB	F	protein heterodimerization activity
GO:0007596	TAS:Reactome	P	blood coagulation
GO:0007160	TAS:ProtInc	P	cell-matrix adhesion
GO:0030198	TAS:Reactome	P	extracellular matrix organization
GO:0007507	IEA:Ensembl	P	heart development
GO:0007229	IEA:UniProtKB-KW	P	integrin-mediated signaling pathway
GO:0050900	TAS:Reactome	P	leukocyte migration
GO:0030324	IMP:UniProtKB	P	lung development
GO:0060135	IEA:Ensembl	P	maternal process involved in female pregnancy
GO:0007613	IEA:Ensembl	P	memory
GO:0048333	IEP:UniProtKB	P	mesodermal cell differentiation
GO:0031345	IEA:Ensembl	P	negative regulation of cell projection organization
GO:0072006	IMP:UniProtKB	P	nephron development
GO:0001764	IEA:Ensembl	P	neuron migration
GO:0010811	IEA:Ensembl	P	positive regulation of cell-substrate adhesion
GO:0010634	IEA:Ensembl	P	positive regulation of epithelial cell migration
GO:0090004	IDA:UniProtKB	P	positive regulation of establishment of protein localization to plasma membrane
GO:0010628	IEA:Ensembl	P	positive regulation of gene expression
GO:0010976	IEA:Ensembl	P	positive regulation of neuron projection development
GO:0030510	IMP:UniProtKB	P	regulation of BMP signaling pathway
GO:0017015	IMP:UniProtKB	P	regulation of transforming growth factor beta receptor signaling pathway
GO:0030111	IMP:UniProtKB	P	regulation of Wnt signaling pathway
GO:0097205	IMP:UniProtKB	P	renal filtration
GO:0042493	IEA:Ensembl	P	response to drug
GO:0034698	IEA:Ensembl	P	response to gonadotropin
GO:0043588	IMP:UniProtKB	P	skin development

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_12560	Basigin interactions
REACT_12051	Cell surface interactions at the vascular wall
REACT_118779	Extracellular matrix organization
REACT_604	Hemostasis
REACT_13552	Integrin cell surface interactions
REACT_169262	Laminin interactions