MGP Database

MGP001670

Ontology/Pathway Information

Entrez Gene ID	3684
Gene Name	integrin, alpha M (complement component 3 receptor 3 subunit)
Gene Symbol	ITGAM
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0009986	IDA:UniProtKB	C	cell surface
GO:0009897	IEA:Ensembl	C	external side of plasma membrane
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0008305	TAS:ProtInc	C	integrin complex
GO:0005634	IEA:Ensembl	C	nucleus
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0001948	IPI:UniProtKB	F	glycoprotein binding
GO:0008201	IEA:Ensembl	F	heparin binding
GO:0046872	IEA:UniProtKB-KW	F	metal ion binding
GO:0050798	IEA:Ensembl	P	activated T cell proliferation
GO:0007596	TAS:Reactome	P	blood coagulation
GO:0007155	TAS:ProtInc	P	cell adhesion
GO:0045123	IEA:Ensembl	P	cellular extravasation
GO:0010668	IEP:UniProtKB	P	ectodermal cell differentiation
GO:0030198	TAS:Reactome	P	extracellular matrix organization
GO:0045087	TAS:Reactome	P	innate immune response
GO:0007229	IEA:UniProtKB-KW	P	integrin-mediated signaling pathway
GO:0007159	IEA:Ensembl	P	leukocyte cell-cell adhesion
GO:0050900	TAS:Reactome	P	leukocyte migration
GO:0002523	IEA:Ensembl	P	leukocyte migration involved in inflammatory response
GO:0014005	IEA:Ensembl	P	microglia development
GO:0030593	IEA:Ensembl	P	neutrophil chemotaxis
GO:0034142	TAS:Reactome	P	toll-like receptor 4 signaling pathway
GO:0002224	TAS:Reactome	P	toll-like receptor signaling pathway

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_12051	Cell surface interactions at the vascular wall
REACT_118779	Extracellular matrix organization
REACT_604	Hemostasis
REACT_6900	Immune System
REACT_6802	Innate Immune System
REACT_13552	Integrin cell surface interactions
REACT_6894	Toll Like Receptor 4 (TLR4) Cascade
REACT_6966	Toll-Like Receptors Cascades