MGP Database

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MGP001676

Ontology/Pathway Information

Entrez Gene ID3693
Gene Nameintegrin, beta 5
Gene Symbol ITGB5
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031252 IEA:EnsemblCcell leading edge
GO:0009986 IDA:UniProtKBCcell surface
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0034684 IDA:UniProtKBCintegrin alphav-beta5 complex
GO:0045335 TAS:ReactomeCphagocytic vesicle
GO:0005886 TAS:ReactomeCplasma membrane
GO:0043235 IDA:MGICreceptor complex
GO:0004872 IEA:InterProFreceptor activity
GO:0042590 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474 TAS:ReactomePantigen processing and presentation of peptide antigen via MHC class I
GO:0007160 IMP:UniProtKBPcell-matrix adhesion
GO:0035987 IEP:UniProtKBPendodermal cell differentiation
GO:0090136 IMP:UniProtKBPepithelial cell-cell adhesion
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0007229 IMP:UniProtKBPintegrin-mediated signaling pathway
GO:0006936 TAS:ReactomePmuscle contraction
GO:0043149 IMP:UniProtKBPstress fiber assembly
GO:0007179 IMP:UniProtKBPtransforming growth factor beta receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_111119Antigen processing-Cross presentation
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_111174Cross-presentation of particulate exogenous antigens (phagosomes)
REACT_163906ECM proteoglycans
REACT_150366Elastic fibre formation
REACT_118779Extracellular matrix organization
REACT_6900Immune System
REACT_13552Integrin cell surface interactions
REACT_150331Molecules associated with elastic fibres
REACT_17044Muscle contraction
REACT_163874Non-integrin membrane-ECM interactions
REACT_20558Smooth Muscle Contraction
REACT_163942Syndecan interactions
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