MGP Database

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MGP001697

Ontology/Pathway Information

Entrez Gene ID3728
Gene Namejunction plakoglobin
Gene Symbol JUP
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0015629 IEA:EnsemblCactin cytoskeleton
GO:0016327 IEA:EnsemblCapicolateral plasma membrane
GO:0016342 IDA:BHF-UCLCcatenin complex
GO:0005913 IDA:UniProtKBCcell-cell adherens junction
GO:0005911 IDA:UniProtKBCcell-cell junction
GO:0005737 IMP:BHF-UCLCcytoplasm
GO:0009898 ISS:BHF-UCLCcytoplasmic side of plasma membrane
GO:0005856 ISS:BHF-UCLCcytoskeleton
GO:0005829 ISS:BHF-UCLCcytosol
GO:0030057 IDA:BHF-UCLCdesmosome
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005916 IEA:EnsemblCfascia adherens
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0071665 IDA:BHF-UCLCgamma-catenin-TCF7L2 complex
GO:0014704 IDA:BHF-UCLCintercalated disc
GO:0005882 IEA:EnsemblCintermediate filament
GO:0016328 IEA:EnsemblClateral plasma membrane
GO:0005634 IMP:BHF-UCLCnucleus
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0032993 IDA:BHF-UCLCprotein-DNA complex
GO:0030018 IEA:EnsemblCZ disc
GO:0005915 ISS:BHF-UCLCzonula adherens
GO:0045294 IPI:BHF-UCLFalpha-catenin binding
GO:0045296 IPI:BHF-UCLFcadherin binding
GO:0042803 ISS:BHF-UCLFprotein homodimerization activity
GO:0019903 IPI:UniProtKBFprotein phosphatase binding
GO:0005199 IC:BHF-UCLFstructural constituent of cell wall
GO:0005198 NAS:BHF-UCLFstructural molecule activity
GO:0003713 IDA:BHF-UCLFtranscription coactivator activity
GO:0034332 TAS:ReactomePadherens junction organization
GO:0086069 IMP:BHF-UCLPbundle of His cell to Purkinje myocyte communication
GO:0045216 TAS:ReactomePcell-cell junction organization
GO:0034329 TAS:ReactomePcell junction assembly
GO:0016477 IMP:BHF-UCLPcell migration
GO:0071681 IDA:UniProtKBPcellular response to indole-3-methanol
GO:0007016 NAS:BHF-UCLPcytoskeletal anchoring at plasma membrane
GO:0002159 IMP:UniProtKBPdesmosome assembly
GO:0050982 IDA:BHF-UCLPdetection of mechanical stimulus
GO:0071603 ISS:BHF-UCLPendothelial cell-cell adhesion
GO:0090002 IMP:UniProtKBPestablishment of protein localization to plasma membrane
GO:0090263 IC:BHF-UCLPpositive regulation of canonical Wnt signaling pathway
GO:0042307 IDA:BHF-UCLPpositive regulation of protein import into nucleus
GO:0051091 IDA:BHF-UCLPpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0051291 IEA:EnsemblPprotein heterooligomerization
GO:0042659 IBA:GO_CentralPregulation of cell fate specification
GO:0042127 IDA:BHF-UCLPregulation of cell proliferation
GO:0086091 IMP:BHF-UCLPregulation of heart rate by cardiac conduction
GO:0016337 IMP:UniProtKBPsingle organismal cell-cell adhesion
GO:0043588 IEA:EnsemblPskin development
GO:0086005 IMP:BHF-UCLPventricular cardiac muscle cell action potential
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_19195Adherens junctions interactions
REACT_111155Cell-Cell communication
REACT_19331Cell-cell junction organization
REACT_20676Cell junction organization
REACT_12529Signaling by VEGF
REACT_111102Signal Transduction
REACT_264464VEGFA-VEGFR2 Pathway
REACT_263991VEGFR2 mediated vascular permeability
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