MGP Database

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MGP001771

UniProt Annotations

Entry Information
Gene Namekiller cell lectin-like receptor subfamily D, member 1
Protein EntryKLRD1_HUMAN
UniProt IDQ13241
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; Synonyms=CD94-A; IsoId=Q13241-1; Sequence=Displayed; Name=2; Synonyms=CD94-B; IsoId=Q13241-2; Sequence=VSP_003053; Name=3; Synonyms=CD94 alt; IsoId=Q13241-3; Sequence=VSP_003052;
FunctionPlays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
SimilarityContains 1 C-type lectin domain. {ECO:0000255|PROSITE- ProRule:PRU00040}.
Subcellular LocationMembrane; Single-pass type II membrane protein.
SubunitCan form disulfide-bonded heterodimer with NKG2 family members. {ECO:0000269|PubMed:18083576, ECO:0000269|PubMed:18332182, ECO:0000269|PubMed:18448674}.
Tissue SpecificityNatural killer cells.
Web ResourceName=Functional Glycomics Gateway - Glycan Binding; Note=CD94; URL="http://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Ctlect_238";
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