MGP Database

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MGP001816

Ontology/Pathway Information

Entrez Gene ID3978
Gene Nameligase I, DNA, ATP-dependent
Gene Symbol LIG1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005694 IBA:GO_CentralCchromosome
GO:0005794 IDA:HPACGolgi apparatus
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0005739 IBA:GO_CentralCmitochondrion
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IBA:GO_CentralCnucleus
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0003677 IEA:InterProFDNA binding
GO:0003909 IDA:UniProtKBFDNA ligase activity
GO:0003910 IEA:UniProtKB-ECFDNA ligase (ATP) activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0009653 TAS:ProtIncPanatomical structure morphogenesis
GO:0006284 IDA:BHF-UCLPbase-excision repair
GO:0051301 IEA:UniProtKB-KWPcell division
GO:0071897 IEA:InterProPDNA biosynthetic process
GO:0051103 IEA:InterProPDNA ligation involved in DNA repair
GO:0006259 TAS:ProtIncPDNA metabolic process
GO:0006310 IEA:UniProtKB-KWPDNA recombination
GO:0006281 TAS:ReactomePDNA repair
GO:0006260 IEA:UniProtKB-KWPDNA replication
GO:0006271 TAS:ReactomePDNA strand elongation involved in DNA replication
GO:0006302 TAS:ReactomePdouble-strand break repair
GO:0000724 TAS:ReactomePdouble-strand break repair via homologous recombination
GO:0006303 IEA:EnsemblPdouble-strand break repair via nonhomologous end joining
GO:0006273 IBA:GO_CentralPlagging strand elongation
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0006289 TAS:ReactomePnucleotide-excision repair
GO:0006297 TAS:ReactomePnucleotide-excision repair, DNA gap filling
GO:0042542 IEA:EnsemblPresponse to hydrogen peroxide
GO:0000723 TAS:ReactomePtelomere maintenance
GO:0000722 TAS:ReactomePtelomere maintenance via recombination
GO:0032201 TAS:ReactomePtelomere maintenance via semi-conservative replication
GO:0006283 TAS:ReactomePtranscription-coupled nucleotide-excision repair
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1104Base Excision Repair
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_22172Chromosome Maintenance
REACT_216DNA Repair
REACT_383DNA Replication
REACT_932DNA strand elongation
REACT_2054Double-Strand Break Repair
REACT_8030Extension of Telomeres
REACT_1998Gap-filling DNA repair synthesis and ligation in GG-NER
REACT_74Gap-filling DNA repair synthesis and ligation in TC-NER
REACT_2253Global Genomic NER (GG-NER)
REACT_1874Homologous Recombination Repair
REACT_1587Homologous recombination repair of replication-independent double-strand breaks
REACT_312Lagging Strand Synthesis
REACT_264442Mismatch Repair
REACT_264347Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
REACT_264501Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
REACT_1826Nucleotide Excision Repair
REACT_8027Processive synthesis on the C-strand of the telomere
REACT_1385Processive synthesis on the lagging strand
REACT_2192Removal of DNA patch containing abasic residue
REACT_1893Resolution of Abasic Sites (AP sites)
REACT_1128Resolution of AP sites via the multiple-nucleotide patch replacement pathway
REACT_2229Resolution of D-loop structures
REACT_977Resolution of D-loop structures through Holliday junction intermediates
REACT_899S Phase
REACT_2014Synthesis of DNA
REACT_7961Telomere C-strand (Lagging Strand) Synthesis
REACT_7970Telomere Maintenance
REACT_1628Transcription-coupled NER (TC-NER)
SMP Pathway Links
SMP IDDescription
SMP00478Nucleotide Excision Repair
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