MGP Database

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MGP001845

Ontology/Pathway Information

Entrez Gene ID4056
Gene Nameleukotriene C4 synthase
Gene Symbol LTC4S
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005783 IDA:UniProtKBCendoplasmic reticulum
GO:0005789 IEA:UniProtKB-SubCellCendoplasmic reticulum membrane
GO:0016021 TAS:ProtIncCintegral component of membrane
GO:0043231 TAS:ProtIncCintracellular membrane-bounded organelle
GO:0005635 IDA:UniProtKBCnuclear envelope
GO:0005640 IEA:UniProtKB-SubCellCnuclear outer membrane
GO:0008047 IEA:InterProFenzyme activator activity
GO:0004602 IBA:GO_CentralFglutathione peroxidase activity
GO:0004364 IBA:GO_CentralFglutathione transferase activity
GO:0004464 IDA:MGIFleukotriene-C4 synthase activity
GO:0008289 IDA:MGIFlipid binding
GO:0019369 TAS:ReactomeParachidonic acid metabolic process
GO:0019370 IBA:GO_CentralPleukotriene biosynthetic process
GO:0006691 IDA:MGIPleukotriene metabolic process
GO:2001300 TAS:ReactomePlipoxin metabolic process
GO:0019372 TAS:ReactomePlipoxygenase pathway
GO:0055114 IBA:GOCPoxidation-reduction process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_147851Arachidonic acid metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_150209Synthesis of 5-eicosatetraenoic acids
REACT_150420Synthesis of Leukotrienes (LT) and Eoxins (EX)
REACT_150320Synthesis of Lipoxins (LX)
SMP Pathway Links
SMP IDDescription
SMP00710Acetaminophen Action Pathway
SMP00083Acetylsalicylic Acid Action Pathway
SMP00692Antipyrine Action Pathway
SMP00693Antrafenine Action Pathway
SMP00075Arachidonic Acid Metabolism
SMP00102Bromfenac Action Pathway
SMP00694Carprofen Action Pathway
SMP00096Celecoxib Action Pathway
SMP00093Diclofenac Action Pathway
SMP00289Diflunisal Action Pathway
SMP00084Etodolac Action Pathway
SMP00695Etoricoxib Action Pathway
SMP00696Fenoprofen Action Pathway
SMP00697Flurbiprofen Action Pathway
SMP00086Ibuprofen Action Pathway
SMP00104Indomethacin Action Pathway
SMP00085Ketoprofen Action Pathway
SMP00098Ketorolac Action Pathway
SMP00353Leukotriene C4 Synthesis Deficiency
SMP00700Lornoxicam Action Pathway
SMP00699Lumiracoxib Action Pathway
SMP00698Magnesium salicylate Action Pathway
SMP00109Mefenamic Acid Action Pathway
SMP00106Meloxicam Action Pathway
SMP00114Nabumetone Action Pathway
SMP00120Naproxen Action Pathway
SMP00702Nepafenac Action Pathway
SMP00113Oxaprozin Action Pathway
SMP00701Phenylbutazone Action Pathway
SMP00077Piroxicam Action Pathway
SMP00087Rofecoxib Action Pathway
SMP00708Salicylate-sodium Action Pathway
SMP00709Salicylic Acid Action Pathway
SMP00707Salsalate Action Pathway
SMP00094Sulindac Action Pathway
SMP00101Suprofen Action Pathway
SMP00706Tenoxicam Action Pathway
SMP00705Tiaprofenic Acid Action Pathway
SMP00704Tolmetin Action Pathway
SMP00703Trisalicylate-choline Action Pathway
SMP00116Valdecoxib Action Pathway
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