MGP Database

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MGP001846

Ontology/Pathway Information

Entrez Gene ID4057
Gene Namelactotransferrin
Gene Symbol LTF
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005634 IDA:UniProtKBCnucleus
GO:0097013 TAS:ReactomeCphagocytic vesicle lumen
GO:0030141 IDA:MGICsecretory granule
GO:0042581 IDA:UniProtKBCspecific granule
GO:0003677 IEA:UniProtKB-KWFDNA binding
GO:0008199 IEA:InterProFferric iron binding
GO:0008201 IDA:MGIFheparin binding
GO:0005506 IDA:UniProtKBFiron ion binding
GO:0043539 IDA:UniProtKBFprotein serine/threonine kinase activator activity
GO:0004252 TAS:ProtIncFserine-type endopeptidase activity
GO:0019731 IDA:UniProtKBPantibacterial humoral response
GO:0019732 IDA:UniProtKBPantifungal humoral response
GO:0060349 IDA:UniProtKBPbone morphogenesis
GO:0006959 TAS:ProtIncPhumoral immune response
GO:0002227 IDA:UniProtKBPinnate immune response in mucosa
GO:0051701 TAS:ReactomePinteraction with host
GO:0033214 TAS:ReactomePiron assimilation by chelation and transport
GO:0006826 IEA:InterProPiron ion transport
GO:0043066 ISS:UniProtKBPnegative regulation of apoptotic process
GO:0031665 IDA:UniProtKBPnegative regulation of lipopolysaccharide-mediated signaling pathway
GO:2001205 ISS:UniProtKBPnegative regulation of osteoclast development
GO:1900229 IDA:UniProtKBPnegative regulation of single-species biofilm formation in or on host organism
GO:2000308 ISS:UniProtKBPnegative regulation of tumor necrosis factor (ligand) superfamily member 11 production
GO:0001503 IEA:UniProtKB-KWPossification
GO:0090382 TAS:ReactomePphagosome maturation
GO:1900159 ISS:UniProtKBPpositive regulation of bone mineralization involved in bone maturation
GO:1902732 IDA:UniProtKBPpositive regulation of chondrocyte proliferation
GO:0043123 IDA:UniProtKBPpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092 IDA:UniProtKBPpositive regulation of NF-kappaB transcription factor activity
GO:0045669 IDA:UniProtKBPpositive regulation of osteoblast differentiation
GO:0033690 IDA:UniProtKBPpositive regulation of osteoblast proliferation
GO:0071902 IDA:UniProtKBPpositive regulation of protein serine/threonine kinase activity
GO:0034145 IMP:UniProtKBPpositive regulation of toll-like receptor 4 signaling pathway
GO:0001817 IDA:UniProtKBPregulation of cytokine production
GO:0032680 IDA:UniProtKBPregulation of tumor necrosis factor production
GO:0052572 TAS:ReactomePresponse to host immune response
GO:0001895 IEP:UniProtKBPretina homeostasis
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75925Amyloids
REACT_116125Disease
REACT_121237Latent infection of Homo sapiens with Mycobacterium tuberculosis
REACT_121118Mtb iron assimilation by chelation
REACT_121256Phagosomal maturation (early endosomal stage)
REACT_121042Response of Mtb to phagocytosis
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