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MGP001853

Record overview

MGPD IDMGP001853
Gene ID4085
SpeciesHomo sapiens (Human)
Gene NameMAD2 mitotic arrest deficient-like 1 (yeast)
Gene Symbol MAD2L1
SynonymsMAD2; HSMAD2;
Alternate namesmitotic spindle assembly checkpoint protein MAD2A; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1; MAD2-like protein 1; mitotic arrest deficient 2-like protein 1; mitotic arrest deficient, yeast, homolog-like 1;
Chromosome4
Map Location4q27
SummaryMAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for MAD2L1

Proteins

mitotic spindle assembly checkpoint protein MAD2A
Refseq ID:NP_002349
Protein GI:4505067
UniProt ID:Q13257
mRNA ID:NM_002358
Length:205
RefSeq Status:
MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLELIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERW
QFDIECDKTAKDDSAPREKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNSEEVRLRSFTTTIHKVNSMVAYK
IPVND
 
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