MGP Database

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MGP001897

Ontology/Pathway Information

Entrez Gene ID4200
Gene Namemalic enzyme 2, NAD(+)-dependent, mitochondrial
Gene Symbol ME2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0005759 IEA:UniProtKB-SubCellCmitochondrial matrix
GO:0005739 IDA:HPACmitochondrion
GO:0009055 TAS:UniProtKBFelectron carrier activity
GO:0004471 TAS:ProtIncFmalate dehydrogenase (decarboxylating) (NAD+) activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0051287 IEA:InterProFNAD binding
GO:0008948 IEA:UniProtKB-ECFoxaloacetate decarboxylase activity
GO:0006108 IEA:InterProPmalate metabolic process
SMP Pathway Links
SMP IDDescription
SMP00196Leigh Syndrome
SMP00558Primary hyperoxaluria II, PH2
SMP00334Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency)
SMP00212Pyruvate Dehydrogenase Complex Deficiency
SMP00559Pyruvate kinase deficiency
SMP00060Pyruvate Metabolism
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