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MGP001922

Record overview

MGPD IDMGP001922
Gene ID4259
SpeciesHomo sapiens (Human)
Gene Namemicrosomal glutathione S-transferase 3
Gene Symbol MGST3
SynonymsGST-III;
Alternate namesmicrosomal glutathione S-transferase 3; microsomal GST-3; microsomal GST-III; microsomal glutathione S-transferase III;
Chromosome1
Map Location1q23
EC Number2.5.1.18
SummaryThis gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.[provided by RefSeq, May 2011]
OrthologsView orthologs and multiple alignments for MGST3

Proteins

microsomal glutathione S-transferase 3
Refseq ID:NP_004519
Protein GI:4758714
UniProt ID:O14880
mRNA ID:NM_004528
Length:152
RefSeq Status:
MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCIQRAHQNTLEVYPPFLFFLAVGGVYHPRIASGLGLAWIVGRVLY
AYGYYTGEPSKRSRGALGSIALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH
 
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