MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP001922

Ontology/Pathway Information

Entrez Gene ID4259
Gene Namemicrosomal glutathione S-transferase 3
Gene Symbol MGST3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0043231 TAS:ProtIncCintracellular membrane-bounded organelle
GO:0016020 IDA:UniProtKBCmembrane
GO:0005635 IBA:GO_CentralCnuclear envelope
GO:0004602 IBA:GO_CentralFglutathione peroxidase activity
GO:0004364 IBA:GO_CentralFglutathione transferase activity
GO:0004601 TAS:ProtIncFperoxidase activity
GO:1901687 TAS:ReactomePglutathione derivative biosynthetic process
GO:0006629 TAS:ProtIncPlipid metabolic process
GO:0055114 IBA:GOCPoxidation-reduction process
GO:0007165 TAS:ProtIncPsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006805 TAS:ReactomePxenobiotic metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_264461Aflatoxin activation and detoxification
REACT_13433Biological oxidations
REACT_267633Defective ACY1 causes encephalopathy
REACT_268587Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
REACT_268321Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
REACT_268129Defective GGT1 causes Glutathionuria (GLUTH)
REACT_267887Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
REACT_268063Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
REACT_268256Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
REACT_267818Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
REACT_268027Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
REACT_268058Defective UGT1A1 causes hyperbilirubinemia
REACT_268618Defective UGT1A4 causes hyperbilirubinemia
REACT_116125Disease
REACT_6926Glutathione conjugation
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_6959Phase II conjugation
  logo