MGP Database

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MGP001943

Ontology/Pathway Information

Entrez Gene ID4321
Gene Namematrix metallopeptidase 12 (macrophage elastase)
Gene Symbol MMP12
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005578 IEA:UniProtKB-SubCellCproteinaceous extracellular matrix
GO:0005509 IEA:InterProFcalcium ion binding
GO:0004175 TAS:UniProtKBFendopeptidase activity
GO:0004222 TAS:UniProtKBFmetalloendopeptidase activity
GO:0008270 TAS:ProtIncFzinc ion binding
GO:0030574 TAS:ReactomePcollagen catabolic process
GO:0022617 TAS:ReactomePextracellular matrix disassembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0060054 IDA:BHF-UCLPpositive regulation of epithelial cell proliferation involved in wound healing
GO:0006508 TAS:ProtIncPproteolysis
GO:0035313 IDA:BHF-UCLPwound healing, spreading of epidermal cells
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_150401Collagen degradation
REACT_118572Degradation of the extracellular matrix
REACT_118779Extracellular matrix organization
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