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MGP001950

Record overview

MGPD IDMGP001950
Gene ID4331
SpeciesHomo sapiens (Human)
Gene NameMNAT CDK-activating kinase assembly factor 1
Gene Symbol MNAT1
SynonymsMAT1; TFB3; CAP35; RNF66;
Alternate namesCDK-activating kinase assembly factor MAT1; CDK7/cyclin-H assembly factor; RING finger protein 66; RING finger protein MAT1; cyclin G1 interacting protein; cyclin-G1-interacting protein; menage a trois 1 (CAK assembly factor); menage a trois homolog 1, cyclin H assembly factor;
Chromosome14
Map Location14q23
SummaryThe protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
OrthologsView orthologs and multiple alignments for MNAT1

Proteins

CDK-activating kinase assembly factor MAT1 isoform 1
Refseq ID:NP_002422
Protein GI:4505225
UniProt ID:P51948
mRNA ID:NM_002431
Length:309
RefSeq Status:
MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLE
EVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQ
HKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDA
FSGLFWQPS
 
CDK-activating kinase assembly factor MAT1 isoform 2
Refseq ID:NP_001171434
Protein GI:295789085
UniProt ID:P51948
mRNA ID:NM_001177963
Length:267
RefSeq Status:
MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLE
EVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELGQHISLAPIHKLE
EALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS
 
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