MGP Database

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MGP001990

Ontology/Pathway Information

Entrez Gene ID4599
Gene NameMX dynamin-like GTPase 1
Gene Symbol MX1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 IDA:UniProtKBCcytosol
GO:0005789 IEA:UniProtKB-SubCellCendoplasmic reticulum membrane
GO:0031965 IDA:HPACnuclear membrane
GO:0048471 IDA:UniProtKBCperinuclear region of cytoplasm
GO:0003924 IEA:InterProFGTPase activity
GO:0005525 TAS:ProtIncFGTP binding
GO:0006915 TAS:ProtIncPapoptotic process
GO:0019221 TAS:ReactomePcytokine-mediated signaling pathway
GO:0006952 TAS:ProtIncPdefense response
GO:0051607 IEA:UniProtKB-KWPdefense response to virus
GO:0045087 TAS:UniProtKBPinnate immune response
GO:0045071 IDA:UniProtKBPnegative regulation of viral genome replication
GO:0034340 TAS:UniProtKBPresponse to type I interferon
GO:0009615 IMP:UniProtKBPresponse to virus
GO:0007165 TAS:ProtIncPsignal transduction
GO:0060337 TAS:ReactomePtype I interferon signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115676Antiviral mechanism by IFN-stimulated genes
REACT_75790Cytokine Signaling in Immune system
REACT_6900Immune System
REACT_25162Interferon alpha/beta signaling
REACT_25229Interferon Signaling
REACT_115831ISG15 antiviral mechanism
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