MGP Database

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MGP002104

Ontology/Pathway Information

Entrez Gene ID4830
Gene NameNME/NM23 nucleoside diphosphate kinase 1
Gene Symbol NME1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 TAS:UniProtKBCcytoplasm
GO:0005829 IDA:UniProtKBCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0005739 IBA:GO_CentralCmitochondrion
GO:0005634 IDA:UniProtKBCnucleus
GO:0032587 IDA:UniProtKBCruffle membrane
GO:0005524 IDA:UniProtKBFATP binding
GO:0004536 IDA:UniProtKBFdeoxyribonuclease activity
GO:0005525 IDA:UniProtKBFGTP binding
GO:0042802 IPI:IntActFidentical protein binding
GO:0000287 IDA:UniProtKBFmagnesium ion binding
GO:0004550 IDA:UniProtKBFnucleoside diphosphate kinase activity
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0043024 IPI:UniProtKBFribosomal small subunit binding
GO:0030154 IEA:UniProtKB-KWPcell differentiation
GO:0006241 IEA:InterProPCTP biosynthetic process
GO:0006308 IDA:GOCPDNA catabolic process
GO:0006897 IEA:UniProtKB-KWPendocytosis
GO:0006183 IEA:InterProPGTP biosynthetic process
GO:0008285 TAS:UniProtKBPnegative regulation of cell proliferation
GO:0007399 IEA:UniProtKB-KWPnervous system development
GO:0015949 TAS:ReactomePnucleobase-containing small molecule interconversion
GO:0055086 TAS:ReactomePnucleobase-containing small molecule metabolic process
GO:0009142 IBA:GO_CentralPnucleoside triphosphate biosynthetic process
GO:0043388 IDA:UniProtKBPpositive regulation of DNA binding
GO:0050679 IMP:HGNCPpositive regulation of epithelial cell proliferation
GO:0006163 IBA:GO_CentralPpurine nucleotide metabolic process
GO:0006220 IBA:GO_CentralPpyrimidine nucleotide metabolic process
GO:0042981 TAS:UniProtKBPregulation of apoptotic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006228 IEA:InterProPUTP biosynthetic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_1698Metabolism of nucleotides
REACT_21330Synthesis and interconversion of nucleotide di- and triphosphates
SMP Pathway Links
SMP IDDescription
SMP00629Adefovir Dipivoxil Metabolism Pathway
SMP00446Gemcitabine Action Pathway
SMP00603Gemcitabine Metabolism Pathway
SMP00649Lamivudine Metabolism Pathway
SMP00630Tenofovir Metabolism Pathway
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