MGP Database

MGP002117

UniProt Annotations

Entry Information
Gene Nameneuropeptide Y
Protein EntryNPY_HUMAN
UniProt IDP01303
SpeciesHuman
Comments
Comment typeDescription
FunctionNPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
PtmThe neuropeptide Y form is cleaved at Pro-30 by the prolyl endopeptidase FAP (seprase) activity (in vitro). {ECO:0000269|PubMed:21314817}.
SimilarityBelongs to the NPY family. {ECO:0000305}.
Subcellular LocationSecreted.
Tissue SpecificityOne of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla.
Web ResourceName=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/NPYID44438ch7p15.html";
Web ResourceName=Wikipedia; Note=Neuropeptide Y entry; URL="http://en.wikipedia.org/wiki/Neuropeptide_Y";
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