MGP Database

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MGP002124

Ontology/Pathway Information

Entrez Gene ID4869
Gene Namenucleophosmin (nucleolar phosphoprotein B23, numatrin)
Gene Symbol NPM1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005813 IDA:UniProtKBCcentrosome
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0016020 IDA:UniProtKBCmembrane
GO:0005730 IDA:UniProtKBCnucleolus
GO:0005654 IDA:UniProtKBCnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0030529 IDA:MGICribonucleoprotein complex
GO:0031616 IDA:UniProtKBCspindle pole centrosome
GO:0042393 IDA:UniProtKBFhistone binding
GO:0051059 IDA:UniProtKBFNF-kappaB binding
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0046982 IMP:UniProtKBFprotein heterodimerization activity
GO:0042803 IDA:UniProtKBFprotein homodimerization activity
GO:0019901 IPI:UniProtKBFprotein kinase binding
GO:0004860 IDA:UniProtKBFprotein kinase inhibitor activity
GO:0043023 IDA:MGIFribosomal large subunit binding
GO:0043024 IDA:MGIFribosomal small subunit binding
GO:0003723 IDA:UniProtKBFRNA binding
GO:0030957 IDA:UniProtKBFTat protein binding
GO:0003713 IDA:UniProtKBFtranscription coactivator activity
GO:0051082 IDA:UniProtKBFunfolded protein binding
GO:0007569 IMP:UniProtKBPcell aging
GO:0034080 TAS:ReactomePCENP-A containing nucleosome assembly
GO:0007098 IMP:UniProtKBPcentrosome cycle
GO:0006281 IDA:UniProtKBPDNA repair
GO:0006886 TAS:UniProtKBPintracellular protein transport
GO:0043066 IDA:UniProtKBPnegative regulation of apoptotic process
GO:0008285 IMP:UniProtKBPnegative regulation of cell proliferation
GO:0010826 IMP:UniProtKBPnegative regulation of centrosome duplication
GO:0044387 IDA:UniProtKBPnegative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0006913 IDA:UniProtKBPnucleocytoplasmic transport
GO:0006334 IDA:UniProtKBPnucleosome assembly
GO:0051092 IMP:UniProtKBPpositive regulation of NF-kappaB transcription factor activity
GO:0045727 IDA:UniProtKBPpositive regulation of translation
GO:0008104 IDA:UniProtKBPprotein localization
GO:0051259 IDA:MGIPprotein oligomerization
GO:0046599 IMP:UniProtKBPregulation of centriole replication
GO:0060735 IDA:UniProtKBPregulation of eIF2 alpha phosphorylation by dsRNA
GO:0032071 IDA:UniProtKBPregulation of endodeoxyribonuclease activity
GO:0060699 IDA:UniProtKBPregulation of endoribonuclease activity
GO:0006950 IMP:UniProtKBPresponse to stress
GO:0042255 TAS:UniProtKBPribosome assembly
GO:0007165 NAS:UniProtKBPsignal transduction
GO:0016032 TAS:ReactomePviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115566Cell Cycle
REACT_22172Chromosome Maintenance
REACT_22186Deposition of new CENPA-containing nucleosomes at the centromere
REACT_116125Disease
REACT_6185HIV Infection
REACT_6288Host Interactions of HIV factors
REACT_6916Interactions of Rev with host cellular proteins
REACT_9395Nuclear import of Rev protein
REACT_22344Nucleosome assembly
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