MGP Database

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MGP002129

Ontology/Pathway Information

Entrez Gene ID4891
Gene Namesolute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
Gene Symbol SLC11A2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0045177 IDA:UniProtKBCapical part of cell
GO:0016324 IDA:UniProtKBCapical plasma membrane
GO:0045178 IDA:UniProtKBCbasal part of cell
GO:0005903 IEA:EnsemblCbrush border
GO:0009986 IDA:UniProtKBCcell surface
GO:0005737 IDA:BHF-UCLCcytoplasm
GO:0031410 IDA:UniProtKBCcytoplasmic vesicle
GO:0005769 IDA:UniProtKBCearly endosome
GO:0005887 IEA:EnsemblCintegral component of plasma membrane
GO:0005770 IDA:UniProtKBClate endosome
GO:0031902 IDA:BHF-UCLClate endosome membrane
GO:0005765 IDA:UniProtKBClysosomal membrane
GO:0005764 IDA:UniProtKBClysosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0005634 IDA:UniProtKBCnucleus
GO:0070826 IDA:UniProtKBCparaferritin complex
GO:0048471 IDA:BHF-UCLCperinuclear region of cytoplasm
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0055037 IDA:UniProtKBCrecycling endosome
GO:0005802 IDA:UniProtKBCtrans-Golgi network
GO:0005773 IMP:BHF-UCLCvacuole
GO:0046870 IEA:EnsemblFcadmium ion binding
GO:0015086 IDA:BHF-UCLFcadmium ion transmembrane transporter activity
GO:0050897 IEA:EnsemblFcobalt ion binding
GO:0015087 IDA:UniProtKBFcobalt ion transmembrane transporter activity
GO:0005507 IEA:EnsemblFcopper ion binding
GO:0005375 IDA:BHF-UCLFcopper ion transmembrane transporter activity
GO:0015093 IDA:BHF-UCLFferrous iron transmembrane transporter activity
GO:0015078 IEA:EnsemblFhydrogen ion transmembrane transporter activity
GO:0022890 IGI:UniProtKBFinorganic cation transmembrane transporter activity
GO:0005506 IEA:EnsemblFiron ion binding
GO:0015094 IDA:BHF-UCLFlead ion transmembrane transporter activity
GO:0030145 IEA:EnsemblFmanganese ion binding
GO:0005384 IDA:BHF-UCLFmanganese ion transmembrane transporter activity
GO:0016151 IEA:EnsemblFnickel cation binding
GO:0015099 IDA:UniProtKBFnickel cation transmembrane transporter activity
GO:0015295 IDA:UniProtKBFsolute:proton symporter activity
GO:0015100 IDA:UniProtKBFvanadium ion transmembrane transporter activity
GO:0008270 IEA:EnsemblFzinc ion binding
GO:0005385 IDA:UniProtKBFzinc ion transmembrane transporter activity
GO:0006919 IDA:UniProtKBPactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070574 IDA:BHF-UCLPcadmium ion transmembrane transport
GO:0098655 IGI:GOCPcation transmembrane transport
GO:0006878 IEA:EnsemblPcellular copper ion homeostasis
GO:0006879 TAS:ReactomePcellular iron ion homeostasis
GO:0071456 IEA:EnsemblPcellular response to hypoxia
GO:0071281 IEA:EnsemblPcellular response to iron ion
GO:0034599 IDA:UniProtKBPcellular response to oxidative stress
GO:0071356 IEA:EnsemblPcellular response to tumor necrosis factor
GO:0006824 IDA:UniProtKBPcobalt ion transport
GO:1902861 IEA:EnsemblPcopper ion import into cell
GO:0035434 IDA:GOCPcopper ion transmembrane transport
GO:0006825 IDA:BHF-UCLPcopper ion transport
GO:0048813 IEA:EnsemblPdendrite morphogenesis
GO:0003032 IEP:UniProtKBPdetection of oxygen
GO:0048821 IEA:EnsemblPerythrocyte development
GO:0070627 IDA:UniProtKBPferrous iron import
GO:0015684 IDA:BHF-UCLPferrous iron transport
GO:0006783 IEA:EnsemblPheme biosynthetic process
GO:0015692 IDA:BHF-UCLPlead ion transport
GO:0007611 IEA:EnsemblPlearning or memory
GO:0071421 IDA:GOCPmanganese ion transmembrane transport
GO:0006828 IDA:BHF-UCLPmanganese ion transport
GO:0060586 IMP:BHF-UCLPmulticellular organismal iron ion homeostasis
GO:0035444 IDA:GOCPnickel cation transmembrane transport
GO:0015675 IDA:UniProtKBPnickel cation transport
GO:0046686 IEA:EnsemblPresponse to cadmium ion
GO:0001666 IEP:UniProtKBPresponse to hypoxia
GO:0010039 IEP:UniProtKBPresponse to iron ion
GO:0010288 IEA:EnsemblPresponse to lead ion
GO:0010042 IEA:EnsemblPresponse to manganese ion
GO:0055085 TAS:ReactomePtransmembrane transport
GO:0015676 IDA:GOCPvanadium ion transport
GO:0071577 IDA:GOCPzinc ion transmembrane transport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_25060Iron uptake and transport
REACT_20547Metal ion SLC transporters
REACT_19118SLC-mediated transmembrane transport
REACT_15518Transmembrane transport of small molecules
REACT_19305Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
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