MGP Database

MGP002162

Ontology/Pathway Information

Entrez Gene ID4986
Gene Nameopioid receptor, kappa 1
Gene Symbol OPRK1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016021 IDA:UniProtKBCintegral component of membrane
GO:0005887 IMP:UniProtKBCintegral component of plasma membrane
GO:0043005 IBA:GO_CentralCneuron projection
GO:0005886 TAS:ReactomeCplasma membrane
GO:0038048 IDA:UniProtKBFdynorphin receptor activity
GO:0042923 IBA:GO_CentralFneuropeptide binding
GO:0004985 IDA:UniProtKBFopioid receptor activity
GO:0007193 TAS:ProtIncPadenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0031635 IDA:UniProtKBPadenylate cyclase-inhibiting opioid receptor signaling pathway
GO:0007610 TAS:ProtIncPbehavior
GO:0051607 IDA:UniProtKBPdefense response to virus
GO:0006955 IDA:UniProtKBPimmune response
GO:0007626 ISS:UniProtKBPlocomotory behavior
GO:0007218 IBA:GO_CentralPneuropeptide signaling pathway
GO:0038003 IDA:UniProtKBPopioid receptor signaling pathway
GO:0007200 ISS:UniProtKBPphospholipase C-activating G-protein coupled receptor signaling pathway
GO:0046877 ISS:UniProtKBPregulation of saliva secretion
GO:0007600 TAS:ProtIncPsensory perception
GO:0019233 ISS:UniProtKBPsensory perception of pain
GO:0007268 TAS:ProtIncPsynaptic transmission
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14819Peptide ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00691Nalbuphine Action Pathway
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