MGP Database

MGP002221

Ontology/Pathway Information

Entrez Gene ID5126
Gene Nameproprotein convertase subtilisin/kexin type 2
Gene Symbol PCSK2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030425 IEA:EnsemblCdendrite
GO:0005615 IDA:BHF-UCLCextracellular space
GO:0016020 IDA:BHF-UCLCmembrane
GO:0043204 IEA:EnsemblCperikaryon
GO:0034774 TAS:ReactomeCsecretory granule lumen
GO:0030133 IEA:UniProtKB-SubCellCtransport vesicle
GO:0004252 IDA:BHF-UCLFserine-type endopeptidase activity
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0034230 ISS:BHF-UCLPenkephalin processing
GO:0030070 IDA:BHF-UCLPinsulin processing
GO:0034231 ISS:BHF-UCLPislet amyloid polypeptide processing
GO:0007399 IEA:EnsemblPnervous system development
GO:0016540 IEA:EnsemblPprotein autoprocessing
GO:0006508 IDA:BHF-UCLPproteolysis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15550Insulin processing
REACT_17015Metabolism of proteins
REACT_160078Peptide hormone metabolism
SMP Pathway Links
SMP IDDescription
SMP006793-Methylthiofentanyl Action Pathway
SMP00413Alfentanil Action Pathway
SMP00685Alvimopan Action Pathway
SMP00674Anileridine Action Pathway
SMP00392Benzocaine Action Pathway
SMP00393Bupivacaine Action Pathway
SMP00684Buprenorphine Action Pathway
SMP00414Carfentanil Action Pathway
SMP00394Chloroprocaine Action Pathway
SMP00424Citalopram Action Pathway
SMP00395Cocaine Action Pathway
SMP00405Codeine Action Pathway
SMP00423Desipramine Action Pathway
SMP00676Dezocine Action Pathway
SMP00396Dibucaine Action Pathway
SMP00689Dihydromorphine Action Pathway
SMP00680Dimethylthiambutene Action Pathway
SMP00675Diphenoxylate Action Pathway
SMP00425Escitalopram Action Pathway
SMP00681Ethylmorphine Action Pathway
SMP00415Fentanyl Action Pathway
SMP00426Fluoxetine Action Pathway
SMP00407Heroin Action Pathway
SMP00411Hydrocodone Action Pathway
SMP00410Hydromorphone Action Pathway
SMP00422Imipramine Action Pathway
SMP00690Ketobemidone Action Pathway
SMP00683Levallorphan Action Pathway
SMP00397Levobupivacaine Action Pathway
SMP00677Levomethadyl Acetate Action Action Pathway
SMP00673Levorphanol Action Pathway
SMP00398Lidocaine (Local Anaesthetic) Action Pathway
SMP00399Mepivacaine Action Pathway
SMP00408Methadone Action Pathway
SMP00678Methadyl Acetate Action Pathway
SMP00406Morphine Action Pathway
SMP00691Nalbuphine Action Pathway
SMP00688Naloxone Action Pathway
SMP00687Naltrexone Action Pathway
SMP00431Nicotine Action Pathway
SMP00400Oxybuprocaine Action Pathway
SMP00409Oxycodone Action Pathway
SMP00412Oxymorphone Action Pathway
SMP00686Pentazocine Action Pathway
SMP00401Prilocaine Action Pathway
SMP00402Procaine Action Pathway
SMP00403Proparacaine Action Pathway
SMP00672Propoxyphene Action Pathway
SMP00416Remifentanil Action Pathway
SMP00404Ropivacaine Action Pathway
SMP00417Sufentanil Action Pathway
SMP00671Tramadol Action Action Pathway
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