MGP Database

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MGP002280

UniProt Annotations

Entry Information
Gene Nameserpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
Protein EntryGDN_HUMAN
UniProt IDP07093
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; IsoId=P07093-1; Sequence=Displayed; Name=2; IsoId=P07093-2; Sequence=VSP_038367; Name=3; IsoId=P07093-3; Sequence=VSP_043668, VSP_038367; Note=No experimental confirmation available.;
FunctionSerine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
SimilarityBelongs to the serpin family. {ECO:0000305}.
Subcellular LocationSecreted, extracellular space.
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