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MGP002283

Record overview

MGPD IDMGP002283
Gene ID5279
SpeciesHomo sapiens (Human)
Gene Namephosphatidylinositol glycan anchor biosynthesis, class C
Gene Symbol PIGC
SynonymsGPI2;
Alternate namesphosphatidylinositol N-acetylglucosaminyltransferase subunit C; PIG-C; phosphatidylinositol-glycan biosynthesis class C protein; phosphatidylinositol-glycan biosynthesis, class C protein;
Chromosome1
Map Location1q23-q25
EC Number2.4.1.198
SummaryThis gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for this gene. A pseudogene on chromosome 11 has also been characterized. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PIGC

Proteins

phosphatidylinositol N-acetylglucosaminyltransferase subunit C
Refseq ID:NP_714969
Protein GI:24430186
UniProt ID:Q92535
mRNA ID:NM_153747
Length:297
RefSeq Status:
MYAQPVTNTKEVKWQKVLYERQPFPDNYVDRRFLEELRKNIHARKYQYWAVVFESSVVIQQLCSVCVFVVIWWYMDEGLLAPHWLLGTGLASSLIGYVLF
DLIDGGEGRKKSGQTRWADLKSALVFITFTYGFSPVLKTLTESVSTDTIYAMSVFMLLGHLIFFDYGANAAIVSSTLSLNMAIFASVCLASRLPRSLHAF
IMVTFAIQIFALWPMLQKKLKACTPRSYVGVTLLFAFSAVGGLLSISAVGAVLFALLLMSISCLCPFYLIRLQLFKENIHGPWDEAEIKEDLSRFLS
 
phosphatidylinositol N-acetylglucosaminyltransferase subunit C
Refseq ID:NP_002633
Protein GI:4505795
UniProt ID:Q92535
mRNA ID:NM_002642
Length:297
RefSeq Status:
Protein sequence is identical to GI:24430186 (mRNA isoform)
 
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