MGP Database

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MGP002298

Ontology/Pathway Information

Entrez Gene ID5300
Gene Namepeptidylprolyl cis/trans isomerase, NIMA-interacting 1
Gene Symbol PIN1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IEA:UniProtKB-SubCellCcytoplasm
GO:0030496 IDA:MGICmidbody
GO:0016607 IEA:UniProtKB-SubCellCnuclear speck
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:BHF-UCLCnucleus
GO:0032794 IPI:BHF-UCLFGTPase activating protein binding
GO:0031434 IPI:BHF-UCLFmitogen-activated protein kinase kinase binding
GO:0003755 IDA:BHF-UCLFpeptidyl-prolyl cis-trans isomerase activity
GO:0050815 IDA:BHF-UCLFphosphoserine binding
GO:0050816 IDA:BHF-UCLFphosphothreonine binding
GO:0007049 IEA:UniProtKB-KWPcell cycle
GO:0019221 TAS:ReactomePcytokine-mediated signaling pathway
GO:0045087 TAS:ReactomePinnate immune response
GO:2000146 IDA:BHF-UCLPnegative regulation of cell motility
GO:0070373 IDA:BHF-UCLPnegative regulation of ERK1 and ERK2 cascade
GO:0030512 IDA:BHF-UCLPnegative regulation of transforming growth factor beta receptor signaling pathway
GO:0032480 TAS:ReactomePnegative regulation of type I interferon production
GO:0001934 IGI:MGIPpositive regulation of protein phosphorylation
GO:0032321 IMP:BHF-UCLPpositive regulation of Rho GTPase activity
GO:0051443 IDA:BHF-UCLPpositive regulation of ubiquitin-protein transferase activity
GO:0000413 IDA:GOCPprotein peptidyl-prolyl isomerization
GO:0032465 IMP:MGIPregulation of cytokinesis
GO:0007088 TAS:ProtIncPregulation of mitosis
GO:0060393 IDA:BHF-UCLPregulation of pathway-restricted SMAD protein phosphorylation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115676Antiviral mechanism by IFN-stimulated genes
REACT_75790Cytokine Signaling in Immune system
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_25229Interferon Signaling
REACT_115831ISG15 antiviral mechanism
REACT_25271Negative regulators of RIG-I/MDA5 signaling
REACT_25359RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
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